Neurological issues in children with COVID-19

JE Lin, A Asfour, TB Sewell, B Hooe, P Pryce… - Neuroscience …, 2021 - Elsevier
JE Lin, A Asfour, TB Sewell, B Hooe, P Pryce, C Earley, MY Shen, M Kerner-Rossi…
Neuroscience letters, 2021Elsevier
Abstract Coronavirus disease 2019 (COVID-19) usually leads to a mild infectious disease
course in children, but serious complications may occur in conjunction with both acute
infection and associated phenomena such as the multisystem inflammatory syndrome in
children (MIS-C). Neurological symptoms, which have been predominantly reported in
adults, range from mild headache to seizure, peripheral neuropathy, stroke, demyelinating
disorders, and encephalopathy. Similar to respiratory and cardiac manifestations of COVID …
Abstract
Coronavirus disease 2019 (COVID-19) usually leads to a mild infectious disease course in children, but serious complications may occur in conjunction with both acute infection and associated phenomena such as the multisystem inflammatory syndrome in children (MIS-C). Neurological symptoms, which have been predominantly reported in adults, range from mild headache to seizure, peripheral neuropathy, stroke, demyelinating disorders, and encephalopathy. Similar to respiratory and cardiac manifestations of COVID-19, neurological complications present differently based on age and underlying comorbidities. This review provides a concise overview of the neurological conditions seen in the context of COVID-19, as well as potential mechanisms and long-term implications of COVID-19 in the pediatric population from literature reviews and primary data collected at NewYork-Presbyterian Morgan Stanley Children's Hospital.
Elsevier